Dr. Edward Cooper shows how to give naloxone (Narcan) to dogs Dr. Edward Cooper: Okay, so the purpose of this video will be to demonstrate how to administer naloxone or Narcan in the event of an opioid overdose. If there was exposure to something like heroin or fentanyl then that can cause a pretty significant impact to any dog, and so the goal would be to try to administer the Narcan as quickly as possible. Most often, what you'll have available is a nasal diffuser like this with the goal that we can kind of insert this into the nose, dispense the Narcan, and it will be absorbed that way. So the best way to accomplish this would be if the patient is compliant, as safely as possible, try to gently tip up the nose, insert the nozzle into the nostril and then depress the activator which will then diffuse the medication into the nose. If that doesn't work within about five minutes or so, you can potentially repeat the dose and try that same process again.