Ohio State screening program aims to identify lung cancers earlier, before it’s too late

Doctor examines a cancerous lung nodule on a CT scan

Lung cancer remains the No. 1 cause of cancer-related death in the United States, accounting for almost 25% of all cancer deaths — more than breast, colon and prostate cancers combined. 

The U.S. Preventive Services Task Force (USPSTF) recommends annual lung cancer screening for people ages 50-80 who have smoked for at least 20 years, but only 5.7% of eligible Americans were screened for lung cancer before the COVID-19 pandemic. 

For many, waiting for lung cancer symptom onset is too late

“For people who are at increased risk for lung cancer due to smoking history, waiting until they experience symptoms — like trouble breathing, a chronic cough or chest pain — will be too late. This is why lung cancer is so deadly. These are often signs that the disease is impacting the airways and has advanced to stage 4, which has fewer treatment options,” says Michael Wert, MD, a pulmonologist and director of the lung cancer screening program at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James). Dr. Wert is also a clinical assistant professor of internal medicine at the Ohio State College of Medicine.

“Lung cancer screening is a critical tool for detecting these cancers in their earliest stages, when they are treatable. I implore anyone who is at increased risk to ask their doctor about this simple screening tool.”

Man taking cancer medication
Steve Porter was living symptom-free when he was diagnosed with lung cancer. Steve’s cancer was detected in its early stages when a CT scan revealed a lung nodule, a small spot in the lung, that can be a sign of developing cancer and often goes undetected.

Lung cancer survivor urges others to get screened 

Steve Porter had recently quit after nearly 50 years of smoking cigarettes. When his doctor suggested starting annual lung cancer screening as a precaution due to his history of smoking, noting that his insurance would cover the test, he didn’t hesitate — “Sure, sounds good.” That was in 2017.

In 2019, the screening test showed a nodule that could be a sign of early cancer, which was monitored closely. Three years later, the nodule had changed enough to warrant a biopsy that confirmed stage I lung cancer. 

“I feel grateful my doctor recommended that lung cancer screening, because it wasn’t something I realized was available to me,” Porter says. “I was always told the earlier you find it, the better your odds of beating it. And it proves that fact here, because it was a slow-growing cancer, and I'm cancer free now, for right now, so that's a good thing.”

He encourages anyone with a significant history of smoking to get screened — and do it now.

Ohio State cancer prevention expert works to ensure more people get lifesaving screenings

“So many people put off screening because they aren’t feeling bad — but if you put it off until you feel sick, it is going to be too late with lung cancer. If you are at high risk because of smoking history, you need to face it. It could save your life,” he says. 

Lung cancer screening is now covered by many insurance plans for individuals who are deemed at higher risk, per USPSTF screening guidelines. 

Doctor conducts a bronchoscopy
Jasleen Pannu, MBBS, conducts a bronchoscopy to examine a nodule in a patient’s lung. By flagging CT scans that incidentally reveal these nodules, which may be early signs of lung cancer, experts at the OSUCCC – James are able to begin potentially lifesaving treatment sooner.

Taking a second look at CT scans offers another window into early lung cancer detection

Screening the highest-risk individuals provides the best chances of identifying lung cancer in its earliest stages, but an imaging test commonly used for detecting injuries and illnesses can also catch the subtle, early signs of lung cancer, say experts at the OSUCCC – James. 

While computed tomography (CT) scans can provide important information to diagnose other illnesses and conditions, these imaging tests can also reveal other unrelated issues, known as “incidental” findings, that raise questions beyond what the physicians were originally looking for.

Immunotherapy’s big promise for changing the way we treat lung cancer

Launched this year as a collaboration of the OSUCCC – James and The Ohio State University Wexner Medical Center, the Lung Nodule Program was established to create a system for capturing incidental chest CT lung nodule findings — with the aid of machine learning tools — to determine which patients need additional evaluation.

Jasleen Pannu, MBBS, clinical assistant professor of internal medicine at The Ohio State College of Medicine, who leads this new effort, estimates that roughly 10% of all lung nodules identified through chest CT scans performed to investigate other conditions are cancerous; however, determining which spots need additional evaluation can be challenging. At a large health system like Ohio State, that could mean 1,000 early-stage lung cancer diagnoses annually. 

“We do not want any of these cases to be missed, so creating a process to pinpoint precisely who may benefit most from a biopsy is critical,” Dr. Pannu says. “It is a balancing act of providing the appropriate level of follow-up testing for each patient while also working within the significant staffing resources needed to gather, assess and triage a large volume of incidental findings in a timely way.” 

Taking charge of your lung health

Lung cancer screening remains the best defense for those at higher risk for lung cancer. In 2021, the USPSTF updated its lung cancer screening recommendations to include annual screening for lung cancer with low-dose CT scans in adults between the ages of 50 to 80 years who have a 20 pack-year smoking history and currently smoke or have quit within the past 15 years. Lung cancer screening is now covered by most insurance plans, but it’s best to check with your provider.

Lung cancer screening saves lives

For more information about lung cancer screening at the OSUCCC – James, click or call 1-800-293-5066.

More information


Related websites

Subscribe. The latest from Ohio State Health & Discovery delivered right to your inbox.


Get articles and stories about health, wellness, medicine, science and education delivered right to your inbox from the experts at Ohio State.

Required fields

Tell us more about yourself

By clicking "Subscribe" you agree to our Terms of Use.
Learn more about how we use your information by reading our Privacy Policy.